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Abstract: This study proposes a theoretical model based on Theory of Planned Behavior (TPB) to help understand the intention as well as the behavior of the consumer which leads to the further decision of utilizing healthcare applications on smartphones in Vietnam. The testing hypothesis process was made on the basis of survey data collected from consumers who experienced smartphone healthcare applications mainly in Hanoi and Ho Chi Minh - the 2 biggest cities in Vietnam. During the study, besides five original variables from the TPB model, the research team attached two new independent variables namely Personal Innovativeness in IT and Trust, which represent the main drives leading to the upcoming trend of healthcare application usage. The result indicates that Trust, Attitude and Perceived Behavioral Control (which is formed by Attitude and Perceived Behavioral Control after measuring data validity), Subjective Norm, Personal Innovativeness in IT are the four factors that have a tremendously positive effect on both the selection and practice in smartphone healthcare applications. The research not only contributes to the literature by investigating the influence of the compatibilities on consumption intention and behavior but its findings also provide valuable insights for government and enterprises to have suitable strategies to reach more users and improve their experience.DOI: http://dx.doi.org/10.51505/ijebmr.2022.6514
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