The main purpose of this study was to explore how innovativeness influences the performance of healthcare units in Kenya. The study specifically sought to determine how the five indicators of innovativeness namely: moving services close to patients, hiring highly skilled workforce, opening up new revenue, standardizing operating procedure and borrowing assets influence the performance of healthcare units in Kenya. To compete effectively, healthcare units must constantly improve their performance by reducing maternal mortality, reducing child mortality and increasing the number of referrals to the healthcare unit. The study adopted a survey research design and the target population were the healthcare units in Nairobi, Kenya. The target population was healthcare units in Nairobi, comprising County Hospitals, Health Centres and Health Clinics totalling to 71 and the sample size was 49. Data was collected using questionnaires and analysed using SPSS and Microsoft Excel. Inferential data analysis was carried out by the use of factor and correlation analysis. Regression models were fitted and hypothesis testing carried out using multiple regression analysis and standard F and t tests. The findings of this study from multiple regression analysis indicated that innovativeness positively influenced performance of healthcare units in Nairobi, Kenya. The study results lead to the conclusion that innovativeness improves the performance of Healthcare units in Kenya. The study recommends that healthcare units should focus on moving services close to patients, hiring highly skilled workforce, opening up new revenue, standardizing operating procedures during service to clients since their practice is necessary to ensure improved performance.