Efficient performance of road infrastructure projects is essential for economic growth and development. Local construction firms experience challenges in completing of the projects within the budgeted cost, time schedule and attaining the desired quality. This paper sought to establish the effects of project resource mobilization on performance of road projects constructed by local firms. The study was carried out in the Lake Basin Region, Kenya that has a total of 41 road infrastructure projects undertaken by local firms. The study concludes that project resource mobilization has a significant effect on performance of road infrastructure projects undertaken by local firms.